Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-in...
Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-induced apoptosis
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London, England: SAGE Publications
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English
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London, England: SAGE Publications
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Hepatoblastoma, the most common type of pediatric liver cancer, is treated with a combination of surgery and chemotherapy. An essential drug in the treatment of hepatoblastoma is doxorubicin, which in high doses is cardiotoxic. This adverse effect is due to downregulation of cardiac expression of transcription factor GATA4, leading in turn to dimin...
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Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-induced apoptosis
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TN_cdi_doaj_primary_oai_doaj_org_article_db218f29d2ac4bceb8c0823dee1a2216
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db218f29d2ac4bceb8c0823dee1a2216
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ISSN
1010-4283
E-ISSN
1423-0380
DOI
10.1177/1010428317695016