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Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-in...

Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db218f29d2ac4bceb8c0823dee1a2216

Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-induced apoptosis

About this item

Full title

Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-induced apoptosis

Publisher

London, England: SAGE Publications

Journal title

Tumor biology, 2017-03, Vol.39 (3), p.101042831769501-1010428317695016

Language

English

Formats

Publication information

Publisher

London, England: SAGE Publications

More information

Scope and Contents

Contents

Hepatoblastoma, the most common type of pediatric liver cancer, is treated with a combination of surgery and chemotherapy. An essential drug in the treatment of hepatoblastoma is doxorubicin, which in high doses is cardiotoxic. This adverse effect is due to downregulation of cardiac expression of transcription factor GATA4, leading in turn to dimin...

Alternative Titles

Full title

Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-induced apoptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_db218f29d2ac4bceb8c0823dee1a2216

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db218f29d2ac4bceb8c0823dee1a2216

Other Identifiers

ISSN

1010-4283

E-ISSN

1423-0380

DOI

10.1177/1010428317695016

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