First PET Imaging Studies With Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzhe...
First PET Imaging Studies With Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease
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Author / Creator
Timothy R. DeGrado PhD , Bradley J. Kemp PhD , Mukesh K. Pandey PhD , Huailei Jiang PhD , Tina M. Gunderson MS , Logan R. Linscheid CNMT , Allison R. Woodwick CNMT , Daniel M. McConnell CNMT , Joel G. Fletcher MD , Geoffrey B. Johnson MD, PhD , Ronald C. Petersen MD, PhD , David S. Knopman MD and Val J. Lowe MD
Publisher
SAGE Publishing
Journal title
Language
English
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Publisher
SAGE Publishing
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Contents
Abnormalities in zinc homeostasis are indicated in many human diseases, including Alzheimer disease (AD). 63 Zn-zinc citrate was developed as a positron emission tomography (PET) imaging probe of zinc transport and used in a first-in-human study in 6 healthy elderly individuals and 6 patients with clinically confirmed AD. Dynamic PET imaging of the...
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Full title
First PET Imaging Studies With Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_db459cb185b1487f9151e88360cd935c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db459cb185b1487f9151e88360cd935c
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E-ISSN
1536-0121
DOI
10.1177/1536012116673793
