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Rational selection of morphological phenotypic traits to extract essential similarities in chemical...

Rational selection of morphological phenotypic traits to extract essential similarities in chemical...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db4d298800e845959bc3281639ca4383

Rational selection of morphological phenotypic traits to extract essential similarities in chemical perturbation in the ergosterol pathway

About this item

Full title

Rational selection of morphological phenotypic traits to extract essential similarities in chemical perturbation in the ergosterol pathway

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-08, Vol.14 (1), p.17093-11, Article 17093

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Terbinafine, fluconazole, and amorolfine inhibit fungal ergosterol synthesis by acting on their target enzymes at different steps in the synthetic pathway, causing the accumulation of various intermediates. We found that the effects of these three in- hibitors on yeast morphology were different. The number of morphological parameters commonly alter...

Alternative Titles

Full title

Rational selection of morphological phenotypic traits to extract essential similarities in chemical perturbation in the ergosterol pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_db4d298800e845959bc3281639ca4383

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db4d298800e845959bc3281639ca4383

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-67634-1

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