Tie2-mediated vascular remodeling by ferritin-based protein C nanoparticles confers antitumor and an...
Tie2-mediated vascular remodeling by ferritin-based protein C nanoparticles confers antitumor and anti-metastatic activities
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Conventional therapeutic approaches for tumor angiogenesis, which are primarily focused on the inhibition of active angiogenesis to starve cancerous cells, target the vascular endothelial growth factor signaling pathway. This aggravates hypoxia within the tumor core and ultimately leads to increased tumor proliferation and metastasis. To overcome t...
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Full title
Tie2-mediated vascular remodeling by ferritin-based protein C nanoparticles confers antitumor and anti-metastatic activities
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TN_cdi_doaj_primary_oai_doaj_org_article_db80f33a15cc4fada2f1b9246ca794b9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db80f33a15cc4fada2f1b9246ca794b9
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ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-020-00952-9
