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Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a hig...

Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a hig...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db933c0d43874f78b25c2f9000538975

Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen

About this item

Full title

Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-03, Vol.12 (1), p.1693-18, Article 1693

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Proteases are among the largest protein families and critical regulators of biochemical processes like apoptosis and blood coagulation. Knowledge of proteases has been expanded by the development of proteomic approaches, however, technology for multiplexed screening of proteases within native environments is currently lacking behind. Here we introd...

Alternative Titles

Full title

Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_db933c0d43874f78b25c2f9000538975

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db933c0d43874f78b25c2f9000538975

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-21754-8

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