Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined wit...
Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade
About this item
Full title
Author / Creator
D’Alise, Anna Morena , Leoni, Guido , Cotugno, Gabriella , Troise, Fulvia , Langone, Francesca , Fichera, Imma , De Lucia, Maria , Avalle, Lidia , Vitale, Rosa , Leuzzi, Adriano , Bignone, Veronica , Di Matteo, Elena , Tucci, Fabio Giovanni , Poli, Valeria , Lahm, Armin , Catanese, Maria Teresa , Folgori, Antonella , Colloca, Stefano , Nicosia, Alfredo and Scarselli, Elisa
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Neoantigens (nAgs) are promising tumor antigens for cancer vaccination with the potential of inducing robust and selective T cell responses. Genetic vaccines based on Adenoviruses derived from non-human Great Apes (GAd) elicit strong and effective T cell-mediated immunity in humans. Here, we investigate for the first time the potency and efficacy o...
Alternative Titles
Full title
Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade
Authors, Artists and Contributors
Author / Creator
Leoni, Guido
Cotugno, Gabriella
Troise, Fulvia
Langone, Francesca
Fichera, Imma
De Lucia, Maria
Avalle, Lidia
Vitale, Rosa
Leuzzi, Adriano
Bignone, Veronica
Di Matteo, Elena
Tucci, Fabio Giovanni
Poli, Valeria
Lahm, Armin
Catanese, Maria Teresa
Folgori, Antonella
Colloca, Stefano
Nicosia, Alfredo
Scarselli, Elisa
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_db93e80d193c417e9e00b2880fe30cbc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db93e80d193c417e9e00b2880fe30cbc
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10594-2