DON in pediatric cerebral malaria, a phase I/IIA dose-escalation safety study: study protocol for a...
DON in pediatric cerebral malaria, a phase I/IIA dose-escalation safety study: study protocol for a clinical trial
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Despite treatment with highly effective antimalarial drugs, malaria annually claims the lives of over half a million children under 5-years of age in sub-Saharan Africa. Cerebral malaria (CM), defined as Plasmodium falciparum infection with coma, is the severe malaria syndrome with the highest mortality. Studies in the CM mouse model suggest that a...
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Full title
DON in pediatric cerebral malaria, a phase I/IIA dose-escalation safety study: study protocol for a clinical trial
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TN_cdi_doaj_primary_oai_doaj_org_article_db9455a78ade4c80b6bcd3739bf6018c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db9455a78ade4c80b6bcd3739bf6018c
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ISSN
1745-6215
E-ISSN
1745-6215
DOI
10.1186/s13063-023-07808-w
