Synthetic microbe communities provide internal reference standards for metagenome sequencing and ana...
Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The complexity of microbial communities, combined with technical biases in next-generation sequencing, pose a challenge to metagenomic analysis. Here, we develop a set of internal DNA standards, termed “sequins” (sequencing spike-ins), that together constitute a synthetic community of artificial microbial genomes. Sequins are added to environmental...
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Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis
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TN_cdi_doaj_primary_oai_doaj_org_article_db9f1c1f4bb54a1cb1792bb0e5f72ff5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_db9f1c1f4bb54a1cb1792bb0e5f72ff5
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05555-0
