A New Class of Benzo[ b ]thiophene-chalcones as Cholinesterase Inhibitors: Synthesis, Biological Eva...
A New Class of Benzo[ b ]thiophene-chalcones as Cholinesterase Inhibitors: Synthesis, Biological Evaluation, Molecular Docking and ADME Studies
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
In this study, heterocyclic compounds containing a benzothiophene scaffold were designed and synthetized, and their inhibitory activity against cholinesterases (ChE) and the viability of SH-SY5Y cells have been evaluated. Benzothiophenes
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and benzothiophene-chalcone hybrids
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were tested against both acetylcholinesterase (AChE) and but...
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Full title
A New Class of Benzo[ b ]thiophene-chalcones as Cholinesterase Inhibitors: Synthesis, Biological Evaluation, Molecular Docking and ADME Studies
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TN_cdi_doaj_primary_oai_doaj_org_article_dc1202973100495e930e7d9fd9df0841
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc1202973100495e930e7d9fd9df0841
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules29163748
