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PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease

PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc6d3204a13b49c5a7219d8cff74ae90

PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease

About this item

Full title

PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease

Publisher

England: BioMed Central Ltd

Journal title

Cell & bioscience, 2012-06, Vol.2 (1), p.23-23, Article 23

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

PDLIM2 is essential for the termination of the inflammatory transcription factors NF-κB and STAT but is dispensable for the development of immune cells and immune tissues/organs. Currently, it remains unknown whether and how PDLIM2 is involved in physiologic and pathogenic processes.
Here we report that naive PDLIM2 deficient CD4+ T cells were p...

Alternative Titles

Full title

PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dc6d3204a13b49c5a7219d8cff74ae90

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc6d3204a13b49c5a7219d8cff74ae90

Other Identifiers

ISSN

2045-3701

E-ISSN

2045-3701

DOI

10.1186/2045-3701-2-23

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