β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leadi...
β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood-brain barrier destruction in Alzheimer's disease
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Author / Creator
Li, Jianhua , Li, Mengyu , Ge, Yangyang , Chen, Jiayi , Ma, Jiamin , Wang, Chenchen , Sun, Miaomiao , Wang, Li , Yao, Shanglong and Yao, Chengye
Publisher
England: BioMed Central
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central
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Scope and Contents
Contents
Blood-brain barrier (BBB) dysfunction may occur at the onset of Alzheimer's disease (AD). Pericytes are a vital part of the neurovascular unit and the BBB, acting as gatekeepers of the BBB. Amyloid β (Aβ) deposition and neurofibrillary tangles in the brain are the central pathological features of AD. CD36 promotes vascular amyloid deposition and le...
Alternative Titles
Full title
β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood-brain barrier destruction in Alzheimer's disease
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_dc8acf8ccfb945548bc8694b9a2a7049
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc8acf8ccfb945548bc8694b9a2a7049
Other Identifiers
ISSN
2045-3701
E-ISSN
2045-3701
DOI
10.1186/s13578-022-00807-5
