A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified...
A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk
About this item
Full title
Author / Creator
Jermy, Bradley , Läll, Kristi , Wolford, Brooke N. , Wang, Ying , Zguro, Kristina , Cheng, Yipeng , Kanai, Masahiro , Kanoni, Stavroula , Yang, Zhiyu , Hartonen, Tuomo , Monti, Remo , Wanner, Julian , Youssef, Omar , Lippert, Christoph , van Heel, David , Okada, Yukinori , McCartney, Daniel L. , Hayward, Caroline , Marioni, Riccardo E. , Furini, Simone , Renieri, Alessandra , Martin, Alicia R. , Neale, Benjamin M. , Hveem, Kristian , Mägi, Reedik , Palotie, Aarno , Heyne, Henrike , Mars, Nina , Ganna, Andrea , Ripatti, Samuli , Estonian Biobank research team and FinnGen
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Polygenic scores (PGSs) offer the ability to predict genetic risk for complex diseases across the life course; a key benefit over short-term prediction models. To produce risk estimates relevant to clinical and public health decision-making, it is important to account for varying effects due to age and sex. Here, we develop a novel framework to est...
Alternative Titles
Full title
A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk
Authors, Artists and Contributors
Author / Creator
Läll, Kristi
Wolford, Brooke N.
Wang, Ying
Zguro, Kristina
Cheng, Yipeng
Kanai, Masahiro
Kanoni, Stavroula
Yang, Zhiyu
Hartonen, Tuomo
Monti, Remo
Wanner, Julian
Youssef, Omar
Lippert, Christoph
van Heel, David
Okada, Yukinori
McCartney, Daniel L.
Hayward, Caroline
Marioni, Riccardo E.
Furini, Simone
Renieri, Alessandra
Martin, Alicia R.
Neale, Benjamin M.
Hveem, Kristian
Mägi, Reedik
Palotie, Aarno
Heyne, Henrike
Mars, Nina
Ganna, Andrea
Ripatti, Samuli
Estonian Biobank research team
FinnGen
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_dc912c91250843ceb044717d0c5c8972
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dc912c91250843ceb044717d0c5c8972
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-48938-2
