Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histon...
Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases
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Author / Creator
Fellows, Rachel , Denizot, Jérémy , Stellato, Claudia , Cuomo, Alessandro , Jain, Payal , Stoyanova, Elena , Balázsi, Szabina , Hajnády, Zoltán , Liebert, Anke , Kazakevych, Juri , Blackburn, Hector , Corrêa, Renan Oliveira , Fachi, José Luís , Sato, Fabio Takeo , Ribeiro, Willian R. , Ferreira, Caroline Marcantonio , Perée, Hélène , Spagnuolo, Mariangela , Mattiuz, Raphaël , Matolcsi, Csaba , Guedes, Joana , Clark, Jonathan , Veldhoen, Marc , Bonaldi, Tiziana , Vinolo, Marco Aurélio Ramirez and Varga-Weisz, Patrick
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The recently discovered histone post-translational modification crotonylation connects cellular metabolism to gene regulation. Its regulation and tissue-specific functions are poorly understood. We characterize histone crotonylation in intestinal epithelia and find that histone H3 crotonylation at lysine 18 is a surprisingly abundant modification i...
Alternative Titles
Full title
Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases
Authors, Artists and Contributors
Author / Creator
Denizot, Jérémy
Stellato, Claudia
Cuomo, Alessandro
Jain, Payal
Stoyanova, Elena
Balázsi, Szabina
Hajnády, Zoltán
Liebert, Anke
Kazakevych, Juri
Blackburn, Hector
Corrêa, Renan Oliveira
Fachi, José Luís
Sato, Fabio Takeo
Ribeiro, Willian R.
Ferreira, Caroline Marcantonio
Perée, Hélène
Spagnuolo, Mariangela
Mattiuz, Raphaël
Matolcsi, Csaba
Guedes, Joana
Clark, Jonathan
Veldhoen, Marc
Bonaldi, Tiziana
Vinolo, Marco Aurélio Ramirez
Varga-Weisz, Patrick
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_dcb0d5694cd141d7940f735b72dfe7cb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dcb0d5694cd141d7940f735b72dfe7cb
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02651-5