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Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histon...

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histon...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dcb0d5694cd141d7940f735b72dfe7cb

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

About this item

Full title

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-01, Vol.9 (1), p.105-15, Article 105

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The recently discovered histone post-translational modification crotonylation connects cellular metabolism to gene regulation. Its regulation and tissue-specific functions are poorly understood. We characterize histone crotonylation in intestinal epithelia and find that histone H3 crotonylation at lysine 18 is a surprisingly abundant modification i...

Alternative Titles

Full title

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dcb0d5694cd141d7940f735b72dfe7cb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dcb0d5694cd141d7940f735b72dfe7cb

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-02651-5

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