Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic prof...
Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study
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Author / Creator
Chen, Erfei , Yang, Fangfang , He, Hongjuan , Li, Qiqi , Zhang, Wei , Xing, Jinliang , Zhu, Ziqing , Jiang, Jingjing , Wang, Hua , Zhao, Xiaojuan , Liu, Ruitao , Lei, Lei , Dong, Jing , Pei, Yuchen , Yang, Ying , Pan, Junqiang , Zhang, Pan , Liu, Shuzhen , Du, Le , Zeng, Yuan and Yang, Jin
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Although the genetic spectrum of human colorectal cancer (CRC) is mainly characterized by APC, KRAS and TP53 mutations, driver genes in tumor initiation have not been conclusively demonstrated. In this study, we aimed to identify novel markers for CRC.
We performed exome analysis of sporadic colorectal cancer (sCRC) coding regions to screen loss...
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Full title
Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study
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TN_cdi_doaj_primary_oai_doaj_org_article_dcc4a19a25b84b14b660957ed1b4a0ae
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dcc4a19a25b84b14b660957ed1b4a0ae
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-018-0925-7
