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Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions

Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dcc95dec92b044f8abc9e1182dca2d13

Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions

About this item

Full title

Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-03, Vol.10 (1), p.1207-12, Article 1207

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In bacteria, transcription-coupled repair of DNA lesions initiates after the Mfd protein removes RNA polymerases (RNAPs) stalled at the lesions. The bacterial RNA helicase, Rho, is a transcription termination protein that dislodges the elongation complexes. Here, we show that Rho dislodges the stalled RNAPs at DNA lesions. Strains defective in both...

Alternative Titles

Full title

Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dcc95dec92b044f8abc9e1182dca2d13

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dcc95dec92b044f8abc9e1182dca2d13

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-09146-5

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