Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions
Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In bacteria, transcription-coupled repair of DNA lesions initiates after the Mfd protein removes RNA polymerases (RNAPs) stalled at the lesions. The bacterial RNA helicase, Rho, is a transcription termination protein that dislodges the elongation complexes. Here, we show that Rho dislodges the stalled RNAPs at DNA lesions. Strains defective in both...
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Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions
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TN_cdi_doaj_primary_oai_doaj_org_article_dcc95dec92b044f8abc9e1182dca2d13
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dcc95dec92b044f8abc9e1182dca2d13
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09146-5