Log in to save to my catalogue

Prion protein alters viral control and enhances pathology after perinatal cytomegalovirus infection

Prion protein alters viral control and enhances pathology after perinatal cytomegalovirus infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dce0d0a6be9b4345b547ef7eba7dc590

Prion protein alters viral control and enhances pathology after perinatal cytomegalovirus infection

About this item

Full title

Prion protein alters viral control and enhances pathology after perinatal cytomegalovirus infection

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-09, Vol.15 (1), p.7754-17, Article 7754

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cytomegalovirus (CMV) infection poses risks to newborns, necessitating effective therapies. Given that the damage includes both viral infection of brain cells and immune system-related damage, here we investigate the involvement of cellular prion protein (PrP), which plays vital roles in neuroprotection and immune regulation. Using a murine model,...

Alternative Titles

Full title

Prion protein alters viral control and enhances pathology after perinatal cytomegalovirus infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dce0d0a6be9b4345b547ef7eba7dc590

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dce0d0a6be9b4345b547ef7eba7dc590

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-51931-4

How to access this item