Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization i...
Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization in vitro
About this item
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Epicardial formation is necessary for normal myocardial morphogenesis. Here, we show that differentiating hiPSC-derived lateral plate mesoderm with BMP4, RA and VEGF (BVR) can generate a premature form of epicardial cells (termed pre-epicardial cells, PECs) expressing
WT1
,
TBX18
,
SEMA3D
, and
SCX
within 7 days. BVR stimula...
Alternative Titles
Full title
Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization in vitro
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TN_cdi_doaj_primary_oai_doaj_org_article_dce68985cbe8407fb378c24f42d8af61
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dce68985cbe8407fb378c24f42d8af61
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24921-z
