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Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans

Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dced9d3e9d5c441eaba1bc9789351905

Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans

About this item

Full title

Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-03, Vol.12 (1), p.1622-16, Article 1622

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Our mathematical model of integration site data in clinical gene therapy supported the existence of long-term lymphoid progenitors capable of surviving independently from hematopoietic stem cells. To date, no experimental setting has been available to validate this prediction. We here report evidence of a population of lymphoid progenitors capable...

Alternative Titles

Full title

Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dced9d3e9d5c441eaba1bc9789351905

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dced9d3e9d5c441eaba1bc9789351905

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-21834-9

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