868 Antibody blockade of the mono-ADP-ribosyltransferase ART1 promotes radiation-induced tumour infi...
868 Antibody blockade of the mono-ADP-ribosyltransferase ART1 promotes radiation-induced tumour infiltration of dendritic cells and potentiates tumour control by radiotherapy and CTLA-4 inhibition
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundHypofractionated radiotherapy (RT) combined with anti-CTLA-4 antibodies has been shown to induce systemic anti-tumour immunity in anti-CTLA-4-refractory metastatic non-small cell lung cancer (NSCLC) patients.1 The immunogenicity of RT relies on its activation of conventional type I dendritic cells (cDC1s) which are essential for cross-pri...
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868 Antibody blockade of the mono-ADP-ribosyltransferase ART1 promotes radiation-induced tumour infiltration of dendritic cells and potentiates tumour control by radiotherapy and CTLA-4 inhibition
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TN_cdi_doaj_primary_oai_doaj_org_article_dceeae956df342608ec904f47954e86f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dceeae956df342608ec904f47954e86f
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E-ISSN
2051-1426
DOI
10.1136/jitc-2023-SITC2023.0868
