Assessing bnAb potency in the context of HIV-1 envelope conformational plasticity
Assessing bnAb potency in the context of HIV-1 envelope conformational plasticity
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
For use in prevention and treatment, HIV-1 broadly neutralizing antibodies (bnAbs) have to overcome Env conformational heterogeneity of viral quasispecies and neutralize with constant high potency. Comparative analysis of neutralization data from the CATNAP database revealed a nuanced relationship between bnAb activity and Env conformational flexib...
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Full title
Assessing bnAb potency in the context of HIV-1 envelope conformational plasticity
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TN_cdi_doaj_primary_oai_doaj_org_article_dd0d82584f014225b37d6d2cb1c3abd6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd0d82584f014225b37d6d2cb1c3abd6
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1012825
