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Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcri...

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd1811100f074ec8a3558e9cc0a6bb45

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

About this item

Full title

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-06, Vol.12 (1), p.3885-13, Article 3885

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cell identity is maintained by activation of cell-specific gene programs, regulated by epigenetic marks, transcription factors and chromatin organization. DNA G-quadruplex (G4)-folded regions in cells were reported to be associated with either increased or decreased transcriptional activity. By G4-ChIP-seq/RNA-seq analysis on liposarcoma cells we c...

Alternative Titles

Full title

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dd1811100f074ec8a3558e9cc0a6bb45

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd1811100f074ec8a3558e9cc0a6bb45

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-24198-2

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