Oxidative stress enhances the therapeutic action of a respiratory inhibitor in MYC‐driven lymphoma
Oxidative stress enhances the therapeutic action of a respiratory inhibitor in MYC‐driven lymphoma
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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MYC is a key oncogenic driver in multiple tumor types, but concomitantly endows cancer cells with a series of vulnerabilities that provide opportunities for targeted pharmacological intervention. For example, drugs that suppress mitochondrial respiration selectively kill MYC‐overexpressing cells. Here, we unravel the mechanistic basis for this synt...
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Oxidative stress enhances the therapeutic action of a respiratory inhibitor in MYC‐driven lymphoma
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TN_cdi_doaj_primary_oai_doaj_org_article_dd1aad8474044a6a872abca328cab2af
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd1aad8474044a6a872abca328cab2af
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.202216910
