Structural basis of ligand interaction with atypical chemokine receptor 3
Structural basis of ligand interaction with atypical chemokine receptor 3
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Chemokines drive cell migration through their interactions with seven-transmembrane (7TM) chemokine receptors on cell surfaces. The atypical chemokine receptor 3 (ACKR3) binds chemokines CXCL11 and CXCL12 and signals exclusively through β-arrestin-mediated pathways, without activating canonical G-protein signalling. This receptor is upregulated in...
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Full title
Structural basis of ligand interaction with atypical chemokine receptor 3
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TN_cdi_doaj_primary_oai_doaj_org_article_dd25b21c34a34084a772b436c75162ce
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd25b21c34a34084a772b436c75162ce
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14135
