Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human...
Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells
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Author / Creator
Bodnar, Brittany , Zhang, Yongang , Liu, Jinbiao , Lin, Yuan , Wang, Peng , Wei, Zhengyu , Saribas, Sami , Zhu, Yuanjun , Li, Fang , Wang, Xu , Yang, Wenli , Li, Qingsheng , Ho, Wen-Zhe and Hu, Wenhui
Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Scope and Contents
Contents
Human cerebral organoid (CO) is a three-dimensional (3D) cell culture system that recapitulates the developing human brain. While CO has proved an invaluable tool for studying neurological disorders in a more clinically relevant matter, there have still been several shortcomings including CO variability and reproducibility as well as lack of or und...
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Full title
Novel Scalable and Simplified System to Generate Microglia-Containing Cerebral Organoids From Human Induced Pluripotent Stem Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_dd2ff4921ce44480a4aebd8ef93fc79d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd2ff4921ce44480a4aebd8ef93fc79d
Other Identifiers
ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2021.682272