SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis
SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Regulation of VEGFR2 represents an important mechanism for the control of angiogenesis. VEGFR2 activity can be regulated by post-translational modifications such as ubiquitination and acetylation. However, whether VEGFR2 can be regulated by SUMOylation has not been investigated. Here we show that endothelial-specific deletion of the SUMO endopeptid...
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Full title
SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_dd3cd77fca9b4bf389b136bb5cc97d80
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd3cd77fca9b4bf389b136bb5cc97d80
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05812-2
