Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice
Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice
About this item
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Author / Creator
Monnerat, Gustavo , Alarcón, Micaela L. , Vasconcellos, Luiz R. , Hochman-Mendez, Camila , Brasil, Guilherme , Bassani, Rosana A. , Casis, Oscar , Malan, Daniela , Travassos, Leonardo H. , Sepúlveda, Marisa , Burgos, Juan Ignacio , Vila-Petroff, Martin , Dutra, Fabiano F. , Bozza, Marcelo T. , Paiva, Claudia N. , Carvalho, Adriana Bastos , Bonomo, Adriana , Fleischmann, Bernd K. , de Carvalho, Antonio Carlos Campos and Medei, Emiliano
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Diabetes mellitus (DM) encompasses a multitude of secondary disorders, including heart disease. One of the most frequent and potentially life threatening disorders of DM-induced heart disease is ventricular tachycardia (VT). Here we show that toll-like receptor 2 (TLR2) and NLRP3 inflammasome activation in cardiac macrophages mediate the production...
Alternative Titles
Full title
Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice
Authors, Artists and Contributors
Author / Creator
Alarcón, Micaela L.
Vasconcellos, Luiz R.
Hochman-Mendez, Camila
Brasil, Guilherme
Bassani, Rosana A.
Casis, Oscar
Malan, Daniela
Travassos, Leonardo H.
Sepúlveda, Marisa
Burgos, Juan Ignacio
Vila-Petroff, Martin
Dutra, Fabiano F.
Bozza, Marcelo T.
Paiva, Claudia N.
Carvalho, Adriana Bastos
Bonomo, Adriana
Fleischmann, Bernd K.
de Carvalho, Antonio Carlos Campos
Medei, Emiliano
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_dd521bbbf78046d888ba049b54d46e2e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd521bbbf78046d888ba049b54d46e2e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms13344
