Oral administration of pyrophosphate inhibits connective tissue calcification
Oral administration of pyrophosphate inhibits connective tissue calcification
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Various disorders including pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI), which are caused by inactivating mutations in
ABCC6
and
ENPP1
, respectively, present with extensive tissue calcification due to reduced plasma pyrophosphate (PPi). However, it has always been assumed that the bioavailabi...
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Oral administration of pyrophosphate inhibits connective tissue calcification
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TN_cdi_doaj_primary_oai_doaj_org_article_dd5aa1b75e9b4bf692423b721ab030b0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dd5aa1b75e9b4bf692423b721ab030b0
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201707532