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CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment

CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dda216b0fc2a4b11a9340849cfc3ea50

CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment

About this item

Full title

CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment

Publisher

London: BioMed Central Ltd

Journal title

Journal of experimental & clinical cancer research, 2023-03, Vol.42 (1), p.1-13, Article 61

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

We recently identified CD46 as a novel prostate cancer cell surface antigen that shows lineage independent expression in both adenocarcinoma and small cell neuroendocrine subtypes of metastatic castration resistant prostate cancer (mCRPC), discovered an internalizing human monoclonal antibody YS5 that binds to a tumor selective CD46 epitope, and de...

Alternative Titles

Full title

CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dda216b0fc2a4b11a9340849cfc3ea50

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dda216b0fc2a4b11a9340849cfc3ea50

Other Identifiers

ISSN

1756-9966,0392-9078

E-ISSN

1756-9966

DOI

10.1186/s13046-023-02636-x

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