Glypican-3 targeted delivery of 89Zr and 90Y as a theranostic radionuclide platform for hepatocellul...
Glypican-3 targeted delivery of 89Zr and 90Y as a theranostic radionuclide platform for hepatocellular carcinoma
About this item
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Author / Creator
Labadie, Kevin P. , Ludwig, Andrew D. , Lehnert, Adrienne L. , Hamlin, Donald K. , Kenoyer, Aimee L. , Sullivan, Kevin M. , Daniel, Sara K. , Mihailovic, Tara N. , Sham, Jonathan G. , Orozco, Johnnie J. , Yeung, Raymond S. , Chen, Delphine L. , Wilbur, D. Scott , Miyaoka, Robert S. and Park, James O.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Glypican-3 (GPC3) is a tumor associated antigen expressed by hepatocellular carcinoma (HCC) cells. This preclinical study evaluated the efficacy of a theranostic platform using a GPC3-targeting antibody αGPC3 conjugated to zirconium-89 (
89
Zr) and yttrium-90 (
90
Y) to identify, treat, and assess treatment response in a murine model of...
Alternative Titles
Full title
Glypican-3 targeted delivery of 89Zr and 90Y as a theranostic radionuclide platform for hepatocellular carcinoma
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ddea22e7449b4b418c2f02ca24983fd2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ddea22e7449b4b418c2f02ca24983fd2
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-82172-w
