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Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced...

Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ddfe357a5c8c476c8210243386f1932f

Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced Neurons

About this item

Full title

Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced Neurons

Publisher

Basel: MDPI AG

Journal title

Biomedicines, 2023-09, Vol.11 (9), p.2564

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

Alzheimer’s disease (AD) is the most prevalent cause of dementia in the elderly, characterized by the presence of amyloid-beta (Aβ) plaques, neurofibrillary tangles, neuroinflammation, synapse loss and neurodegeneration in the brain. The amyloid cascade hypothesis postulates that deposition of Aβ peptides is the causative agent of AD pathology, but...

Alternative Titles

Full title

Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced Neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ddfe357a5c8c476c8210243386f1932f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ddfe357a5c8c476c8210243386f1932f

Other Identifiers

ISSN

2227-9059

E-ISSN

2227-9059

DOI

10.3390/biomedicines11092564

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