Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced...
Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced Neurons
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Basel: MDPI AG
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English
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Basel: MDPI AG
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Alzheimer’s disease (AD) is the most prevalent cause of dementia in the elderly, characterized by the presence of amyloid-beta (Aβ) plaques, neurofibrillary tangles, neuroinflammation, synapse loss and neurodegeneration in the brain. The amyloid cascade hypothesis postulates that deposition of Aβ peptides is the causative agent of AD pathology, but...
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Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced Neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_ddfe357a5c8c476c8210243386f1932f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ddfe357a5c8c476c8210243386f1932f
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ISSN
2227-9059
E-ISSN
2227-9059
DOI
10.3390/biomedicines11092564