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Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxov...

Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxov...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de04deb85ee9444f8080c1d3da9a63d7

Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence

About this item

Full title

Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-10, Vol.8 (1), p.799-13, Article 799

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Replication defective viral genomes (DVGs) generated during virus replication are the primary triggers of antiviral immunity in many RNA virus infections. However, DVGs can also facilitate viral persistence. Why and how these two opposing functions of DVGs are achieved remain unknown. Here we report that during Sendai and respiratory syncytial viru...

Alternative Titles

Full title

Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_de04deb85ee9444f8080c1d3da9a63d7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de04deb85ee9444f8080c1d3da9a63d7

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-00909-6

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