Molecular mechanisms of the CdnG-Cap5 antiphage defense system employing 3′,2′-cGAMP as the second m...
Molecular mechanisms of the CdnG-Cap5 antiphage defense system employing 3′,2′-cGAMP as the second messenger
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cyclic-oligonucleotide-based antiphage signaling systems (CBASS) are diverse and abundant in bacteria. Here, we present the biochemical and structural characterization of two CBASS systems, composed of CdnG and Cap5, from
Asticcacaulis sp
. and
Lactococcus lactis
. We show that CdnG from
Asticcacaulis sp
. synthesizes 3′,2′-cGAMP...
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Full title
Molecular mechanisms of the CdnG-Cap5 antiphage defense system employing 3′,2′-cGAMP as the second messenger
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TN_cdi_doaj_primary_oai_doaj_org_article_de1e461a293446d0a6357b4dd12aedbc
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de1e461a293446d0a6357b4dd12aedbc
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-26738-2
