Multi-country evaluation of RISK6, a 6-gene blood transcriptomic signature, for tuberculosis diagnos...
Multi-country evaluation of RISK6, a 6-gene blood transcriptomic signature, for tuberculosis diagnosis and treatment monitoring
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Author / Creator
Bayaa, Rim , Ndiaye, Mame Diarra Bousso , Chedid, Carole , Kokhreidze, Eka , Tukvadze, Nestani , Banu, Sayera , Uddin, Mohammad Khaja Mafij , Biswas, Samanta , Nasrin, Rumana , Ranaivomanana, Paulo , Raherinandrasana, Antso Hasina , Rakotonirina, Julio , Rasolofo, Voahangy , Delogu, Giovanni , De Maio, Flavio , Goletti, Delia , Endtz, Hubert , Ader, Florence , Hamze, Monzer , Ismail, Mohamad Bachar , Pouzol, Stéphane , Rakotosamimanana, Niaina , Hoffmann, Jonathan and The HINTT working group within the GABRIEL network
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
There is a crucial need for non-sputum-based TB tests. Here, we evaluate the performance of RISK6, a human-blood transcriptomic signature, for TB screening, triage and treatment monitoring. RISK6 performance was also compared to that of two IGRAs: one based on RD1 antigens (QuantiFERON-TB Gold Plus, QFT-P, Qiagen) and one on recombinant
M. tuber...
Alternative Titles
Full title
Multi-country evaluation of RISK6, a 6-gene blood transcriptomic signature, for tuberculosis diagnosis and treatment monitoring
Authors, Artists and Contributors
Author / Creator
Ndiaye, Mame Diarra Bousso
Chedid, Carole
Kokhreidze, Eka
Tukvadze, Nestani
Banu, Sayera
Uddin, Mohammad Khaja Mafij
Biswas, Samanta
Nasrin, Rumana
Ranaivomanana, Paulo
Raherinandrasana, Antso Hasina
Rakotonirina, Julio
Rasolofo, Voahangy
Delogu, Giovanni
De Maio, Flavio
Goletti, Delia
Endtz, Hubert
Ader, Florence
Hamze, Monzer
Ismail, Mohamad Bachar
Pouzol, Stéphane
Rakotosamimanana, Niaina
Hoffmann, Jonathan
The HINTT working group within the GABRIEL network
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_de33777566a645f5adea0e0e7f01b111
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de33777566a645f5adea0e0e7f01b111
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-93059-1
