FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis
About this item
Full title
Author / Creator
Shamsi, Farnaz , Xue, Ruidan , Huang, Tian Lian , Lundh, Morten , Liu, Yang , Leiria, Luiz O. , Lynes, Matthew D. , Kempf, Elena , Wang, Chih-Hao , Sugimoto, Satoru , Nigro, Pasquale , Landgraf, Kathrin , Schulz, Tim , Li, Yiming , Emanuelli, Brice , Kothakota, Srinivas , Williams, Lewis T. , Jessen, Niels , Pedersen, Steen Bønløkke , Böttcher, Yvonne , Blüher, Matthias , Körner, Antje , Goodyear, Laurie J. , Mohammadi, Moosa , Kahn, C. Ronald and Tseng, Yu-Hua
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Uncoupling protein-1 (UCP1) plays a central role in energy dissipation in brown adipose tissue (BAT). Using high-throughput library screening of secreted peptides, we identify two fibroblast growth factors (FGF), FGF6 and FGF9, as potent inducers of UCP1 expression in adipocytes and preadipocytes. Surprisingly, this occurs through a mechanism indep...
Alternative Titles
Full title
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis
Authors, Artists and Contributors
Author / Creator
Xue, Ruidan
Huang, Tian Lian
Lundh, Morten
Liu, Yang
Leiria, Luiz O.
Lynes, Matthew D.
Kempf, Elena
Wang, Chih-Hao
Sugimoto, Satoru
Nigro, Pasquale
Landgraf, Kathrin
Schulz, Tim
Li, Yiming
Emanuelli, Brice
Kothakota, Srinivas
Williams, Lewis T.
Jessen, Niels
Pedersen, Steen Bønløkke
Böttcher, Yvonne
Blüher, Matthias
Körner, Antje
Goodyear, Laurie J.
Mohammadi, Moosa
Kahn, C. Ronald
Tseng, Yu-Hua
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_de377e337a5a402280aaea762fc97cbe
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de377e337a5a402280aaea762fc97cbe
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15055-9
