RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin
RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The small GTPase ARL8 associates with endolysosomes, leading to the recruitment of several effectors that couple endolysosomes to kinesins for anterograde transport along microtubules, and to tethering factors for eventual fusion with other organelles. Herein we report the identification of the
RU
N- and
FY
VE-domain-containing proteins...
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RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin
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TN_cdi_doaj_primary_oai_doaj_org_article_de5673f787304fe384e3b17410c143de
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de5673f787304fe384e3b17410c143de
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28952-y