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Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors

Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de65f32784d1411784fc7aff84287e18

Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors

About this item

Full title

Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2018-02, Vol.23 (2), p.337

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Multidrug resistance (MDR) is a phenotype of cancer cells with reduced sensitivity to a wide range of unrelated drugs. P-glycoprotein (P-gp)—a drug efflux pump (ABCB1 member of the ABC transporter gene family)—is frequently observed to be a molecular cause of MDR. The drug-efflux activity of P-gp is considered as the underlying mechanism of drug re...

Alternative Titles

Full title

Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_de65f32784d1411784fc7aff84287e18

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de65f32784d1411784fc7aff84287e18

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules23020337

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