Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like...
Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion
About this item
Full title
Author / Creator
Wang, Xiaobo , Istvanffy, Rouzanna , Ye, Linhan , Teller, Steffen , Laschinger, Melanie , Diakopoulos, Kalliope N. , Görgülü, Kıvanç , Li, Qiaolin , Ren, Lei , Jäger, Carsten , Steiger, Katja , Muckenhuber, Alexander , Vilne, Baiba , Çifcibaşı, Kaan , Reyes, Carmen Mota , Yurteri, Ümmügülsüm , Kießler, Maximilian , Gürçınar, Ibrahim Halil , Sugden, Maya , Yıldızhan, Saliha Elif , Sezerman, Osman Uğur , Çilingir, Sümeyye , Süyen, Güldal , Reichert, Maximilian , Schmid, Roland M. , Bärthel, Stefanie , Oellinger, Rupert , Krüger, Achim , Rad, Roland , Saur, Dieter , Algül, Hana , Friess, Helmut , Lesina, Marina , Ceyhan, Güralp Onur and Demir, Ihsan Ekin
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Solid cancers like pancreatic ductal adenocarcinoma (PDAC), a type of pancreatic cancer, frequently exploit nerves for rapid dissemination. This neural invasion (NI) is an independent prognostic factor in PDAC, but insufficiently modeled in genetically engineered mouse models (GEMM) of PDAC. Here, we systematically screened for human-like NI in Eur...
Alternative Titles
Full title
Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion
Authors, Artists and Contributors
Author / Creator
Istvanffy, Rouzanna
Ye, Linhan
Teller, Steffen
Laschinger, Melanie
Diakopoulos, Kalliope N.
Görgülü, Kıvanç
Li, Qiaolin
Ren, Lei
Jäger, Carsten
Steiger, Katja
Muckenhuber, Alexander
Vilne, Baiba
Çifcibaşı, Kaan
Reyes, Carmen Mota
Yurteri, Ümmügülsüm
Kießler, Maximilian
Gürçınar, Ibrahim Halil
Sugden, Maya
Yıldızhan, Saliha Elif
Sezerman, Osman Uğur
Çilingir, Sümeyye
Süyen, Güldal
Reichert, Maximilian
Schmid, Roland M.
Bärthel, Stefanie
Oellinger, Rupert
Krüger, Achim
Rad, Roland
Saur, Dieter
Algül, Hana
Friess, Helmut
Lesina, Marina
Ceyhan, Güralp Onur
Demir, Ihsan Ekin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_de6bfa94aa5043158c58f7d898718cfc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de6bfa94aa5043158c58f7d898718cfc
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI166333
