Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related neurode...
Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related neurodegenerative deficits
About this item
Full title
Author / Creator
Laguna, Ariadna , Peñuelas, Núria , Gonzalez-Sepulveda, Marta , Nicolau, Alba , Arthaud, Sébastien , Guillard-Sirieix, Camille , Lorente-Picón, Marina , Compte, Joan , Miquel-Rio, Lluís , Xicoy, Helena , Liu, Jiong , Parent, Annabelle , Cuadros, Thais , Romero-Giménez, Jordi , Pujol, Gemma , Giménez-Llort, Lydia , Fort, Patrice , Bortolozzi, Analia , Carballo-Carbajal, Iria and Vila, Miquel
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
One key limitation in developing effective treatments for neurodegenerative diseases is the lack of models accurately mimicking the complex physiopathology of the human disease. Humans accumulate with age the pigment neuromelanin inside neurons that synthesize catecholamines. Neurons reaching the highest neuromelanin levels preferentially degenerat...
Alternative Titles
Full title
Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related neurodegenerative deficits
Authors, Artists and Contributors
Author / Creator
Peñuelas, Núria
Gonzalez-Sepulveda, Marta
Nicolau, Alba
Arthaud, Sébastien
Guillard-Sirieix, Camille
Lorente-Picón, Marina
Compte, Joan
Miquel-Rio, Lluís
Xicoy, Helena
Liu, Jiong
Parent, Annabelle
Cuadros, Thais
Romero-Giménez, Jordi
Pujol, Gemma
Giménez-Llort, Lydia
Fort, Patrice
Bortolozzi, Analia
Carballo-Carbajal, Iria
Vila, Miquel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_de9a8ae5677146419f7bcb8a1fa18b31
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_de9a8ae5677146419f7bcb8a1fa18b31
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-53168-7
