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Single-cell transcriptome profiling highlights the importance of telocyte, kallikrein genes, and alt...

Single-cell transcriptome profiling highlights the importance of telocyte, kallikrein genes, and alt...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_deb4ba5ced5b4522976f75db58d88667

Single-cell transcriptome profiling highlights the importance of telocyte, kallikrein genes, and alternative splicing in mouse testes aging

About this item

Full title

Single-cell transcriptome profiling highlights the importance of telocyte, kallikrein genes, and alternative splicing in mouse testes aging

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-06, Vol.14 (1), p.14795-14, Article 14795

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Advancing healthcare for elderly men requires a deeper understanding of testicular aging processes. In this study, we conducted transcriptomic profiling of 43,323 testicular single cells from young and old mice, shedding light on 1032 telocytes—an underexplored testicular cell type in previous research. Our study unveiled 916 age-related differenti...

Alternative Titles

Full title

Single-cell transcriptome profiling highlights the importance of telocyte, kallikrein genes, and alternative splicing in mouse testes aging

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_deb4ba5ced5b4522976f75db58d88667

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_deb4ba5ced5b4522976f75db58d88667

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-65710-0

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