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DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protecti...

DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protecti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dec1ebc23ee2448fb7ad32d2457e1b56

DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2

About this item

Full title

DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-10, Vol.13 (1), p.5886-16, Article 5886

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Monoclonal antibody therapy has played an important role against SARS-CoV-2. Strategies to deliver functional, antibody-based therapeutics with improved in vivo durability are needed to supplement current efforts and reach underserved populations. Here, we compare recombinant mAbs COV2-2196 and COV2-2130, which compromise clinical cocktail Tixagevi...

Alternative Titles

Full title

DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dec1ebc23ee2448fb7ad32d2457e1b56

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dec1ebc23ee2448fb7ad32d2457e1b56

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-33309-6

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