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AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting...

AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dece29d9a99c41a1ac18844da0b47c18

AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity

About this item

Full title

AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity

Publisher

England: BioMed Central

Journal title

Journal of neuroinflammation, 2017-12, Vol.14 (1), p.246-246, Article 246

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

N-arachidonoylphenolamine (AM404), a paracetamol metabolite, is a potent agonist of the transient receptor potential vanilloid type 1 (TRPV1) and low-affinity ligand of the cannabinoid receptor type 1 (CB1). There is evidence that AM404 exerts its pharmacological effects in immune cells. However, the effect of AM404 on the production of inflammator...

Alternative Titles

Full title

AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dece29d9a99c41a1ac18844da0b47c18

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dece29d9a99c41a1ac18844da0b47c18

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/s12974-017-1014-3

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