AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting...
AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity
About this item
Full title
Author / Creator
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
Subjects
More information
Scope and Contents
Contents
N-arachidonoylphenolamine (AM404), a paracetamol metabolite, is a potent agonist of the transient receptor potential vanilloid type 1 (TRPV1) and low-affinity ligand of the cannabinoid receptor type 1 (CB1). There is evidence that AM404 exerts its pharmacological effects in immune cells. However, the effect of AM404 on the production of inflammator...
Alternative Titles
Full title
AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_dece29d9a99c41a1ac18844da0b47c18
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dece29d9a99c41a1ac18844da0b47c18
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-017-1014-3