Constrained hidden Markov models for population-based haplotyping
Constrained hidden Markov models for population-based haplotyping
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Haplotype Reconstruction is the problem of resolving the hidden phase information in genotype data obtained from laboratory measurements. Solving this problem is an important intermediate step in gene association studies, which seek to uncover the genetic basis of complex diseases. We propose a novel approach for haplotype reconstruction based on c...
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Constrained hidden Markov models for population-based haplotyping
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TN_cdi_doaj_primary_oai_doaj_org_article_dee44a2a0f464b93b53100c9fba80393
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dee44a2a0f464b93b53100c9fba80393
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ISSN
1471-2105
E-ISSN
1471-2105
DOI
10.1186/1471-2105-8-S2-S9