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The antiviral drug telaprevir induces cell death by reducing FOXA1 expression in estrogen receptor α...

The antiviral drug telaprevir induces cell death by reducing FOXA1 expression in estrogen receptor α...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_df0cb0cbff104a4dbfc6b97b3e99803e

The antiviral drug telaprevir induces cell death by reducing FOXA1 expression in estrogen receptor α (ERα)‐positive breast cancer cells

About this item

Full title

The antiviral drug telaprevir induces cell death by reducing FOXA1 expression in estrogen receptor α (ERα)‐positive breast cancer cells

Publisher

Hoboken: John Wiley & Sons, Inc

Journal title

Molecular oncology, 2022-10, Vol.16 (19), p.3568-3584

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Previously, we found that telaprevir (Tel), the inhibitor of hepatitis C virus NS3/4A serine protease, reduces estrogen receptor α (ERα) content at the transcriptional level without binding to the receptor, prevents ERα transcriptional activity, and inhibits basal and 17β‐estradiol (E2)‐dependent cell proliferation in different breast cancer (BC) c...

Alternative Titles

Full title

The antiviral drug telaprevir induces cell death by reducing FOXA1 expression in estrogen receptor α (ERα)‐positive breast cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_df0cb0cbff104a4dbfc6b97b3e99803e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_df0cb0cbff104a4dbfc6b97b3e99803e

Other Identifiers

ISSN

1574-7891

E-ISSN

1878-0261

DOI

10.1002/1878-0261.13303

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