Short-course radiotherapy combined with CAPOX and Toripalimab for the total neoadjuvant therapy of l...
Short-course radiotherapy combined with CAPOX and Toripalimab for the total neoadjuvant therapy of locally advanced rectal cancer: a randomized, prospective, multicentre, double-arm, phase II trial (TORCH)
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Author / Creator
Wang, Yaqi , Shen, Lijun , Wan, Juefeng , Zhang, Hui , Wu, Ruiyan , Wang, Jingwen , Wang, Yan , Xu, Ye , Cai, Sanjun , Zhang, Zhen and Xia, Fan
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
For patients with locally advanced (T3-4/N +) rectal cancer (LARC), the standard treatment is neoadjuvant chemoradiotherapy combined with total mesorectal resection, which greatly decreases local recurrence but does not improve overall survival. For patients who achieve a complete clinical response (cCR) after nCRT, a "Watch & Wait" (W&W) approach...
Alternative Titles
Full title
Short-course radiotherapy combined with CAPOX and Toripalimab for the total neoadjuvant therapy of locally advanced rectal cancer: a randomized, prospective, multicentre, double-arm, phase II trial (TORCH)
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_df43c36e252048eaac3804d48a056962
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_df43c36e252048eaac3804d48a056962
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-022-09348-z