The troglitazone derivative EP13 disrupts energy metabolism through respiratory chain complex I inhi...
The troglitazone derivative EP13 disrupts energy metabolism through respiratory chain complex I inhibition in breast cancer cells and potentiates the antiproliferative effect of glycolysis inhibitors
About this item
Full title
Author / Creator
Publisher
BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
BioMed Central
Subjects
More information
Scope and Contents
Contents
BACKGROUNDThe metabolism of cancer cells generally differs from that of normal cells. Indeed, most cancer cells have a high rate of glycolysis, even at normal oxygen concentrations. These metabolic properties can potentially be exploited for therapeutic intervention. In this context, we have developed troglitazone derivatives to treat hormone-sensi...
Alternative Titles
Full title
The troglitazone derivative EP13 disrupts energy metabolism through respiratory chain complex I inhibition in breast cancer cells and potentiates the antiproliferative effect of glycolysis inhibitors
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_df48bf1c5b36421992cca27a0273fe28
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_df48bf1c5b36421992cca27a0273fe28
Other Identifiers
ISSN
1475-2867
E-ISSN
1475-2867
DOI
10.1186/s12935-024-03319-z
