LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation
LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation
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Author / Creator
Cao, Feng , Li, Zhe , Ding, Wen-Mao , Yan, Ling and Zhao, Qing-Yan
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Long non-coding RNAs (lncRNA) plasmacytoma variant translocation 1 (PVT1) has been shown to be associated with liver fibrosis. Nevertheless, the role of PVT1 in atrial fibrosis remains undefined. This study aims to elucidate the pathophysiological role of lncRNA PVT1 in the regulation of atrial fibrosis and to explore the underlying mechanism.
E...
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Full title
LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation
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TN_cdi_doaj_primary_oai_doaj_org_article_df91e05fbeb74bf6a14a7a289271bedd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_df91e05fbeb74bf6a14a7a289271bedd
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ISSN
1076-1551
E-ISSN
1528-3658
DOI
10.1186/s10020-019-0074-5