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Differential upregulation of AU-rich element-containing mRNAs in COVID-19

Differential upregulation of AU-rich element-containing mRNAs in COVID-19

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dfabde5d889f4cc88972b3d535e917f9

Differential upregulation of AU-rich element-containing mRNAs in COVID-19

About this item

Full title

Differential upregulation of AU-rich element-containing mRNAs in COVID-19

Publisher

England: BioMed Central Ltd

Journal title

Human Genomics, 2022-11, Vol.16 (1), p.59-59, Article 59

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

AU-rich elements (AREs) are located in the 3'UTRs of 22% of human mRNAs, including most transiently expressed inflammatory mediators. By default, AREs mark mRNAs for decay and translational inhibition, but this activity can be temporarily inhibited in case of infection to allow the onset of inflammation. Morbidity and mortality in COVID-19 patients...

Alternative Titles

Full title

Differential upregulation of AU-rich element-containing mRNAs in COVID-19

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dfabde5d889f4cc88972b3d535e917f9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dfabde5d889f4cc88972b3d535e917f9

Other Identifiers

ISSN

1479-7364,1473-9542

E-ISSN

1479-7364

DOI

10.1186/s40246-022-00433-9

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