Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site
About this item
Full title
Author / Creator
Mendes, Vitor , Green, Simon R. , Evans, Joanna C. , Hess, Jeannine , Blaszczyk, Michal , Spry, Christina , Bryant, Owain , Cory-Wright, James , Chan, Daniel S-H. , Torres, Pedro H. M. , Wang, Zhe , Nahiyaan, Navid , O’Neill, Sandra , Damerow, Sebastian , Post, John , Bayliss, Tracy , Lynch, Sasha L. , Coyne, Anthony G. , Ray, Peter C. , Abell, Chris , Rhee, Kyu Y. , Boshoff, Helena I. M. , Barry, Clifton E. , Mizrahi, Valerie , Wyatt, Paul G. and Blundell, Tom L.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Coenzyme A (CoA) is a fundamental co-factor for all life, involved in numerous metabolic pathways and cellular processes, and its biosynthetic pathway has raised substantial interest as a drug target against multiple pathogens including
Mycobacterium tuberculosis
. The biosynthesis of CoA is performed in five steps, with the second and third...
Alternative Titles
Full title
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site
Authors, Artists and Contributors
Author / Creator
Green, Simon R.
Evans, Joanna C.
Hess, Jeannine
Blaszczyk, Michal
Spry, Christina
Bryant, Owain
Cory-Wright, James
Chan, Daniel S-H.
Torres, Pedro H. M.
Wang, Zhe
Nahiyaan, Navid
O’Neill, Sandra
Damerow, Sebastian
Post, John
Bayliss, Tracy
Lynch, Sasha L.
Coyne, Anthony G.
Ray, Peter C.
Abell, Chris
Rhee, Kyu Y.
Boshoff, Helena I. M.
Barry, Clifton E.
Mizrahi, Valerie
Wyatt, Paul G.
Blundell, Tom L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_dfbd7ac1fa2f42d49910fcdc7940c42e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dfbd7ac1fa2f42d49910fcdc7940c42e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20224-x
