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Mutagenesis facilitated crystallization of GLP-1R

Mutagenesis facilitated crystallization of GLP-1R

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dfc11f5493104f83aa57e261a0b1bcd7

Mutagenesis facilitated crystallization of GLP-1R

About this item

Full title

Mutagenesis facilitated crystallization of GLP-1R

Publisher

England: International Union of Crystallography

Journal title

IUCrJ, 2019-11, Vol.6 (6), p.996-1006

Language

English

Formats

Publication information

Publisher

England: International Union of Crystallography

More information

Scope and Contents

Contents

The class B family of G-protein-coupled receptors (GPCRs) has long been a paradigm for peptide hormone recognition and signal transduction. One class B GPCR, the glucagon-like peptide-1 receptor (GLP-1R), has been considered as an anti-diabetes drug target and there are several peptidic drugs available for the treatment of this overwhelming disease...

Alternative Titles

Full title

Mutagenesis facilitated crystallization of GLP-1R

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dfc11f5493104f83aa57e261a0b1bcd7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dfc11f5493104f83aa57e261a0b1bcd7

Other Identifiers

ISSN

2052-2525

E-ISSN

2052-2525

DOI

10.1107/S2052252519013496

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