Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of...
Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer
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Author / Creator
Wang, Meng , Li, Yue , Xiao, Yunyun , Yang, Muwen , Chen, Jinxin , Jian, Yunting , Chen, Xin , Shi, Dongni , Chen, Xiangfu , Ouyang, Ying , Kong, Lingzhi , Huang, Xinjian , Bai, Jiewen , Lin, Chuyong and Song, Libing
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Nicotine addiction and the occurrence of lymph node spread are two major significant factors associated with esophageal cancer’s poor prognosis; however, nicotine’s role in inducing lymphatic metastasis of esophageal cancer remains unclear. Here we show that OTU domain-containing protein 3 (OTUD3) is downregulated by nicotine and correlates with po...
Alternative Titles
Full title
Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_dfd2bc9a8b564fdb8190206a2f1ea75e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dfd2bc9a8b564fdb8190206a2f1ea75e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27348-8
